Spader's roles in the early 1990s included a young, affluent widower opposite Susan Sarandon in the romantic drama White Palace (1990), Rob Lowe in the Noir drama Bad Influence (1990), John Cusack's best friend in the drama True Colors (1991), and a poker-playing drifter in The Music of Chance (1993).
In 1994, he starred as Egyptologist Daniel Jackson in the sci-fi film Stargate.
Spader met his first wife, decorator Victoria Kheel, while working in a yoga studio after he moved to New York City in the 1980s.
From 2004 to 2008, Spader starred as Alan Shore in the series Boston Legal, in which he reprised his role from the television series The Practice.
He won the Emmy Award for Outstanding Lead Actor in a Drama Series in 2004 for his portrayal on The Practice and won it again in 20 for Boston Legal.
He has also done the voice-over in several television commercials for Acura.
Spader stars in the NBC series The Blacklist, which premiered on NBC September 23, 2013.
In 2000, he played a drug-addicted detective tracking down a serial killer in The Watcher.
In 2002, he starred as a sadistic boss in Secretary.
Grant says, "I knew from the tips of my toes that he was unlike anybody I had ever met.
I was just so overwhelmed by him as a person that I finally came up behind him and wrapped my arms around him and said, ' I've needed to do this all night.'" Grant's interest in Gill caught her off guard, and she didn't know what she was going to do about it.
During his early education, he attended multiple private schools, including The Pike School, where his mother taught art, and the Brooks School in North Andover, Massachusetts, where his father taught.
Spader's first major film role was in the film Endless Love (1981), and his first starring role was in Tuff Turf (1985).
In 1996, he played car accident fetishist James Ballard in the controversial Canadian film Crash and assassin Lee Woods in 2 Days in the Valley.